Human Cytomegalovirus Infection Induces Rapamycin-Insensitive Phosphorylation of Downstream Effectors of mTOR Kinase

Signaling mediated by the cellular kinase mammalian target of rapamycin (mTOR) activates cap-dependent translation under normal (nonstressed) conditions. However, translation is inhibited by cellular stress responses or rapamycin treatment, which inhibit mTOR kinase activity. We show that during hum...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Kudchodkar, Sagar B., Yu, Yongjun, Maguire, Tobi G., Alwine, James C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2004
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521827/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15452223/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.20.11030-11039.2004
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