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Dynein mediates the localization and activation of mTOR in normal and human cytomegalovirus-infected cells

Activation of stress signaling pathways normally leads to inhibition of the mammalian target of rapamycin complex 1 (mTORC1); however, human cytomegalovirus (HCMV) infection maintains mTORC1 activity in the presence of numerous types of stress. We previously demonstrated that HCMV infection maintain...

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Detalhes bibliográficos
Main Authors: Clippinger, Amy J., Alwine, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444728/
https://ncbi.nlm.nih.gov/pubmed/22987636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.196147.112
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