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AMPK-Mediated Inhibition of mTOR Kinase Is Circumvented during Immediate-Early Times of Human Cytomegalovirus Infection
Human cytomegalovirus (HCMV) infection increases synthetic rates in infected cells. The resulting increase in energy utilization could potentially increase the AMP:ATP ratio, causing activation of 5′-AMP-activated protein kinase (AMPK). Activated AMPK promotes inhibition of mammalian target of rapam...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1866081/ https://ncbi.nlm.nih.gov/pubmed/17215282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02079-06 |
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