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Glutamine Metabolism Is Essential for Human Cytomegalovirus Infection

Human fibroblasts infected with human cytomegalovirus (HCMV) were more viable than uninfected cells during glucose starvation, suggesting that an alternate carbon source was used. We have determined that infected cells require glutamine for ATP production, whereas uninfected cells do not. This sugge...

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Detalhes bibliográficos
Main Authors: Chambers, Jeremy W., Maguire, Tobi G., Alwine, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812398/
https://ncbi.nlm.nih.gov/pubmed/19939921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02123-09
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