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Glutamine Metabolism Is Essential for Human Cytomegalovirus Infection

Human fibroblasts infected with human cytomegalovirus (HCMV) were more viable than uninfected cells during glucose starvation, suggesting that an alternate carbon source was used. We have determined that infected cells require glutamine for ATP production, whereas uninfected cells do not. This sugge...

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Bibliografiske detaljer
Main Authors: Chambers, Jeremy W., Maguire, Tobi G., Alwine, James C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812398/
https://ncbi.nlm.nih.gov/pubmed/19939921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02123-09
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