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Lovastatin induces VSMC differentiation through inhibition of Rheb and mTOR

It is becoming increasingly clear that cholesterol-independent effects of statins also contribute to the cardioprotective effects, but these mechanisms remain poorly understood. We investigated the effects of lovastatin on vascular smooth muscle phenotype. We have previously shown that mammalian tar...

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Detalhes bibliográficos
Main Authors: Wagner, Robert J., Martin, Kathleen A., Powell, Richard J., Rzucidlo, Eva M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904260/
https://ncbi.nlm.nih.gov/pubmed/20375271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00429.2009
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