Role of Mitochondrial RNA Polymerase in the Toxicity of Nucleotide Inhibitors of Hepatitis C Virus

Toxicity has emerged during the clinical development of many but not all nucleotide inhibitors (NI) of hepatitis C virus (HCV). To better understand the mechanism for adverse events, clinically relevant HCV NI were characterized in biochemical and cellular assays, including assays of decreased viabi...

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Opis bibliograficzny
Wydane w:Antimicrob Agents Chemother
Główni autorzy: Feng, Joy Y., Xu, Yili, Barauskas, Ona, Perry, Jason K., Ahmadyar, Shekeba, Stepan, George, Yu, Helen, Babusis, Darius, Park, Yeojin, McCutcheon, Krista, Perron, Michel, Schultz, Brian E., Sakowicz, Roman, Ray, Adrian S.
Format: Artigo
Język:Inglês
Wydane: American Society for Microbiology 2016
Hasła przedmiotowe:
Antiviral Agents
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750701/
https://ncbi.nlm.nih.gov/pubmed/26596942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01922-15
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