Role of Mitochondrial RNA Polymerase in the Toxicity of Nucleotide Inhibitors of Hepatitis C Virus

Toxicity has emerged during the clinical development of many but not all nucleotide inhibitors (NI) of hepatitis C virus (HCV). To better understand the mechanism for adverse events, clinically relevant HCV NI were characterized in biochemical and cellular assays, including assays of decreased viabi...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Feng, Joy Y., Xu, Yili, Barauskas, Ona, Perry, Jason K., Ahmadyar, Shekeba, Stepan, George, Yu, Helen, Babusis, Darius, Park, Yeojin, McCutcheon, Krista, Perron, Michel, Schultz, Brian E., Sakowicz, Roman, Ray, Adrian S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2016
主題:
Antiviral Agents
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750701/
https://ncbi.nlm.nih.gov/pubmed/26596942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01922-15
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