Minimal hepatic glucose-6-phosphatase-α activity required to sustain survival and prevent hepatocellular adenoma formation in murine glycogen storage disease type Ia

Glycogen storage disease type Ia (GSD-Ia), characterized by impaired glucose homeostasis and chronic risk of hepatocellular adenoma (HCA), is caused by a deficiency in glucose-6-phosphatase-α (G6Pase-α or G6PC) activity. In a previous 70–90 week-study, we showed that a recombinant adeno-associated v...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Genet Metab Rep
Main Authors: Lee, Young Mok, Kim, Goo-Young, Pan, Chi-Jiunn, Mansfield, Brian C., Chou, Janice Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
SI:Therapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750588/
https://ncbi.nlm.nih.gov/pubmed/26937391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgmr.2015.03.001
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados