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Activation of tumor-promoting pathways implicated in hepatocellular adenoma/carcinoma, a long-term complication of glycogen storage disease type Ia

Hepatocellular adenoma/carcinoma (HCA/HCC) is a long-term complication of the metabolic disorder glycogen storage disease type Ia (GSD-Ia) deficient in glucose-6-phosphatase-α (G6PC or G6Pase-α). We have shown previously that hepatic G6Pase-α deficiency leads to autophagy impairment, mitochondrial d...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Cho, Jun-Ho, Lee, Young Mok, Bae, Seong-Ho, Chou, Janice Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954303/
https://ncbi.nlm.nih.gov/pubmed/31735334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2019.11.061
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