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Gene therapy blockade of dorsal striatal p11 improves motor function and dyskinesia in parkinsonian mice
Complications of dopamine replacement for Parkinson’s disease (PD) can limit therapeutic options, leading to interest in identifying novel pathways that can be exploited to improve treatment. p11 (S100A10) is a cellular scaffold protein that binds to and potentiates the activity of various ion chann...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4747714/ https://ncbi.nlm.nih.gov/pubmed/26787858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524387113 |
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