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Molecular adaptations of striatal spiny projection neurons during levodopa-induced dyskinesia

Levodopa treatment is the major pharmacotherapy for Parkinson's disease. However, almost all patients receiving levodopa eventually develop debilitating involuntary movements (dyskinesia). Although it is known that striatal spiny projection neurons (SPNs) are involved in the genesis of this mov...

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Detalhes bibliográficos
Main Authors: Heiman, Myriam, Heilbut, Adrian, Francardo, Veronica, Kulicke, Ruth, Fenster, Robert J., Kolaczyk, Eric D., Mesirov, Jill P., Surmeier, Dalton J., Cenci, M. Angela, Greengard, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970487/
https://ncbi.nlm.nih.gov/pubmed/24599591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401819111
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