Molecular adaptations of striatal spiny projection neurons during levodopa-induced dyskinesia

Levodopa treatment is the major pharmacotherapy for Parkinson's disease. However, almost all patients receiving levodopa eventually develop debilitating involuntary movements (dyskinesia). Although it is known that striatal spiny projection neurons (SPNs) are involved in the genesis of this mov...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Heiman, Myriam, Heilbut, Adrian, Francardo, Veronica, Kulicke, Ruth, Fenster, Robert J., Kolaczyk, Eric D., Mesirov, Jill P., Surmeier, Dalton J., Cenci, M. Angela, Greengard, Paul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2014
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970487/
https://ncbi.nlm.nih.gov/pubmed/24599591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401819111
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