A Subpopulation of Striatal Neurons Mediates Levodopa-Induced Dyskinesia

Parkinson’s disease is characterized by the progressive loss of midbrain dopamine neurons. Dopamine replacement therapy with levodopa alleviates parkinsonian motor symptoms but is complicated by the development of involuntary movements, termed levodopa-induced dyskinesia (LID). Aberrant activity in...

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Udgivet i:Neuron
Main Authors: Girasole, Allison E., Lum, Matthew Y., Nathaniel, Diane, Bair-Marshall, Chloe J., Guenthner, Casey J., Luo, Liqun, Kreitzer, Anatol C., Nelson, Alexandra B.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233726/
https://ncbi.nlm.nih.gov/pubmed/29398356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.01.017
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