A Subpopulation of Striatal Neurons Mediates Levodopa-Induced Dyskinesia

Parkinson’s disease is characterized by the progressive loss of midbrain dopamine neurons. Dopamine replacement therapy with levodopa alleviates parkinsonian motor symptoms but is complicated by the development of involuntary movements, termed levodopa-induced dyskinesia (LID). Aberrant activity in...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Girasole, Allison E., Lum, Matthew Y., Nathaniel, Diane, Bair-Marshall, Chloe J., Guenthner, Casey J., Luo, Liqun, Kreitzer, Anatol C., Nelson, Alexandra B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233726/
https://ncbi.nlm.nih.gov/pubmed/29398356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.01.017
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