Gene therapy blockade of dorsal striatal p11 improves motor function and dyskinesia in parkinsonian mice

Complications of dopamine replacement for Parkinson’s disease (PD) can limit therapeutic options, leading to interest in identifying novel pathways that can be exploited to improve treatment. p11 (S100A10) is a cellular scaffold protein that binds to and potentiates the activity of various ion chann...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Marongiu, Roberta, Arango-Lievano, Margarita, Francardo, Veronica, Morgenstern, Peter, Zhang, Xiaoqun, Cenci, M. Angela, Svenningsson, Per, Greengard, Paul, Kaplitt, Michael G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2016
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747714/
https://ncbi.nlm.nih.gov/pubmed/26787858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524387113
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