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Gene therapy blockade of dorsal striatal p11 improves motor function and dyskinesia in parkinsonian mice
Complications of dopamine replacement for Parkinson’s disease (PD) can limit therapeutic options, leading to interest in identifying novel pathways that can be exploited to improve treatment. p11 (S100A10) is a cellular scaffold protein that binds to and potentiates the activity of various ion chann...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4747714/ https://ncbi.nlm.nih.gov/pubmed/26787858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524387113 |
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