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Folding and assembly of the large molecular machine Hsp90 studied in single-molecule experiments

Folding of small proteins often occurs in a two-state manner and is well understood both experimentally and theoretically. However, many proteins are much larger and often populate misfolded states, complicating their folding process significantly. Here we study the complete folding and assembly pro...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Jahn, Markus, Buchner, Johannes, Hugel, Thorsten, Rief, Matthias
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747692/
https://ncbi.nlm.nih.gov/pubmed/26787848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1518827113
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