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Folding and assembly of the large molecular machine Hsp90 studied in single-molecule experiments

Folding of small proteins often occurs in a two-state manner and is well understood both experimentally and theoretically. However, many proteins are much larger and often populate misfolded states, complicating their folding process significantly. Here we study the complete folding and assembly pro...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Jahn, Markus, Buchner, Johannes, Hugel, Thorsten, Rief, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747692/
https://ncbi.nlm.nih.gov/pubmed/26787848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1518827113
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