Strong male bias drives germline mutation in chimpanzees

Germline mutation determines rates of molecular evolution, genetic diversity, and fitness load. In humans, the average point mutation rate is 1.2 × 10(−8) per base pair per generation, with every additional year of father’s age contributing two mutations across the genome and males contributing thre...

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Bibliographic Details
Published in:	Science
Main Authors:	Venn, Oliver, Turner, Isaac, Mathieson, Iain, de Groot, Natasja, Bontrop, Ronald, McVean, Gil
Format:	Artigo
Language:	Inglês
Published:	2014
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4746749/ https://ncbi.nlm.nih.gov/pubmed/24926018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.344.6189.1272
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Strong male bias drives germline mutation in chimpanzees

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