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Estimating Selection Coefficients in Spatially Structured Populations from Time Series Data of Allele Frequencies

Inferring the nature and magnitude of selection is an important problem in many biological contexts. Typically when estimating a selection coefficient for an allele, it is assumed that samples are drawn from a panmictic population and that selection acts uniformly across the population. However, the...

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Detalhes bibliográficos
Main Authors: Mathieson, Iain, McVean, Gil
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584010/
https://ncbi.nlm.nih.gov/pubmed/23307902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.147611
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