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Estimating Selection Coefficients in Spatially Structured Populations from Time Series Data of Allele Frequencies

Inferring the nature and magnitude of selection is an important problem in many biological contexts. Typically when estimating a selection coefficient for an allele, it is assumed that samples are drawn from a panmictic population and that selection acts uniformly across the population. However, the...

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Autori principali: Mathieson, Iain, McVean, Gil
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584010/
https://ncbi.nlm.nih.gov/pubmed/23307902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.147611
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