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Estimation of Natural Selection and Allele Age from Time Series Allele Frequency Data Using a Novel Likelihood-Based Approach

Temporally spaced genetic data allow for more accurate inference of population genetic parameters and hypothesis testing on the recent action of natural selection. In this work, we develop a novel likelihood-based method for jointly estimating selection coefficient and allele age from time series da...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: He, Zhangyi, Dai, Xiaoyang, Beaumont, Mark, Yu, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7536852/
https://ncbi.nlm.nih.gov/pubmed/32769100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.120.303400
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