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Estimating Selection Coefficients in Spatially Structured Populations from Time Series Data of Allele Frequencies

Inferring the nature and magnitude of selection is an important problem in many biological contexts. Typically when estimating a selection coefficient for an allele, it is assumed that samples are drawn from a panmictic population and that selection acts uniformly across the population. However, the...

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Hlavní autoři: Mathieson, Iain, McVean, Gil
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584010/
https://ncbi.nlm.nih.gov/pubmed/23307902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.147611
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