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Demography and the Age of Rare Variants

Large whole-genome sequencing projects have provided access to much rare variation in human populations, which is highly informative about population structure and recent demography. Here, we show how the age of rare variants can be estimated from patterns of haplotype sharing and how these ages can...

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Dades bibliogràfiques
Autors principals: Mathieson, Iain, McVean, Gil
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125085/
https://ncbi.nlm.nih.gov/pubmed/25101869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004528
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