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What drives recombination hotspots to repeat DNA in humans?

Recombination between homologous, but non-allelic, stretches of DNA such as gene families, segmental duplications and repeat elements is an important source of mutation. In humans, recent studies have identified short DNA motifs that both determine the location of 40 per cent of meiotic cross-over h...

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Detalhes bibliográficos
Autor principal: McVean, Gil
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871820/
https://ncbi.nlm.nih.gov/pubmed/20308096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2009.0299
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