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What drives recombination hotspots to repeat DNA in humans?

Recombination between homologous, but non-allelic, stretches of DNA such as gene families, segmental duplications and repeat elements is an important source of mutation. In humans, recent studies have identified short DNA motifs that both determine the location of 40 per cent of meiotic cross-over h...

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Dades bibliogràfiques
Autor principal: McVean, Gil
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871820/
https://ncbi.nlm.nih.gov/pubmed/20308096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2009.0299
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