Stable recombination hotspots in birds

The DNA-binding protein PRDM9 has a critical role in specifying meiotic recombination hotspots in mice and apes, but appears to be absent from other vertebrate species, including birds. To study the evolution and determinants of recombination in species lacking PRDM9, we inferred fine-scale genetic...

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Publicat a:Science
Autors principals: Singhal, Sonal, Leffler, Ellen M., Sannareddy, Keerthi, Turner, Isaac, Venn, Oliver, Hooper, Daniel M., Strand, Alva I., Li, Qiye, Raney, Brian, Balakrishnan, Christopher N., Griffith, Simon C., McVean, Gil, Przeworski, Molly
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864528/
https://ncbi.nlm.nih.gov/pubmed/26586757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad0843
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