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Stable recombination hotspots in birds

The DNA-binding protein PRDM9 has a critical role in specifying meiotic recombination hotspots in mice and apes, but appears to be absent from other vertebrate species, including birds. To study the evolution and determinants of recombination in species lacking PRDM9, we inferred fine-scale genetic...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Singhal, Sonal, Leffler, Ellen M., Sannareddy, Keerthi, Turner, Isaac, Venn, Oliver, Hooper, Daniel M., Strand, Alva I., Li, Qiye, Raney, Brian, Balakrishnan, Christopher N., Griffith, Simon C., McVean, Gil, Przeworski, Molly
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864528/
https://ncbi.nlm.nih.gov/pubmed/26586757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad0843
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