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Yersinia effector YopO uses actin as bait to phosphorylate proteins that regulate actin polymerization

Pathogenic Yersinia species evade host immune systems through the injection of Yersinia outer proteins (Yops) into phagocytic cells. One Yop, YopO, also known as YpkA, induces actin-filament disruption, impairing phagocytosis. Here we describe the X-ray structure of Yersinia enterocolitica YopO in c...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Nat Struct Mol Biol
Asıl Yazarlar: Lee, Wei Lin, Grimes, Jonathan M, Robinson, Robert C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745138/
https://ncbi.nlm.nih.gov/pubmed/25664724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2964
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