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Yersinia effector YopO uses actin as bait to phosphorylate proteins that regulate actin polymerization

Pathogenic Yersinia species evade host immune systems through the injection of Yersinia outer proteins (Yops) into phagocytic cells. One Yop, YopO, also known as YpkA, induces actin-filament disruption, impairing phagocytosis. Here we describe the X-ray structure of Yersinia enterocolitica YopO in c...

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Vydáno v:Nat Struct Mol Biol
Hlavní autoři: Lee, Wei Lin, Grimes, Jonathan M, Robinson, Robert C
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745138/
https://ncbi.nlm.nih.gov/pubmed/25664724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2964
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