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Protection from Genital Herpes Disease, Seroconversion, and Latent Infection in a Non-lethal Murine Genital Infection Model by Immunization with an HSV-2 Replication-Defective Mutant Virus

Viral vaccines have traditionally protected against disease, but for viruses that establish latent infection, it is desirable for the vaccine to reduce infection to reduce latent infection and reactivation. While seroconversion has been used in clinical trials of herpes simplex virus (HSV) vaccines...

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Publicado en:Virology
Main Authors: Diaz, Fernando M., Knipe, David M.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744556/
https://ncbi.nlm.nih.gov/pubmed/26609935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.10.033
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