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Immunization with a Replication-Defective Herpes Simplex Virus 2 Mutant Reduces Herpes Simplex Virus 1 Infection and Prevents Ocular Disease

Ocular infections with herpes simplex virus lead to corneal scarring and blindness, with herpes keratitis being the major infectious cause of blindness. There is currently no clinically approved vaccine and nearly all developmental vaccines are targeted against HSV-2 and genital herpes. We tested th...

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Detalhes bibliográficos
Main Authors: van Lint, Allison L., Torres-Lopez, Ernesto, Knipe, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099303/
https://ncbi.nlm.nih.gov/pubmed/17915278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.08.030
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