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Protection from Herpes Simplex Virus (HSV) 2 Infection with Replication-Defective HSV-2 or Glycoprotein D2 Vaccines in HSV-1 Seropositive and Seronegative Guinea Pigs
BACKGROUND: A herpes simplex virus (HSV) 2 candidate vaccine consisting of glycoprotein D (gD2) in alum and monophosphoryl lipid A (MPL) reduced genital herpes disease in HSV-1 seronegative women, but not in men or HSV-1 seropositive women. METHODS: To determine the effect of HSV-1 serostatus on eff...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3826825/ https://ncbi.nlm.nih.gov/pubmed/19702506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/605645 |
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