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Intermediates in the assembly of mitotic checkpoint complexes and their role in the regulation of the anaphase-promoting complex
The mitotic (or spindle assembly) checkpoint system prevents premature separation of sister chromatids in mitosis and thus ensures the fidelity of chromosome segregation. Kinetochores that are not attached properly to the mitotic spindle produce an inhibitory signal that prevents progression into an...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4743829/ https://ncbi.nlm.nih.gov/pubmed/26755599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524551113 |
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