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Role of Polo-like kinase 1 in the regulation of the action of p31(comet) in the disassembly of mitotic checkpoint complexes

The Mad2-binding protein p31(comet) has important roles in the inactivation of the mitotic checkpoint system, which delays anaphase until chromosomes attach correctly to the mitotic spindle. The activation of the checkpoint promotes the assembly of a Mitotic Checkpoint Complex (MCC), which inhibits...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Kaisari, Sharon, Shomer, Pnina, Ziv, Tamar, Sitry-Shevah, Danielle, Miniowitz-Shemtov, Shirly, Teichner, Adar, Hershko, Avram
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575526/
https://ncbi.nlm.nih.gov/pubmed/31118282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902970116
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