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Role of Polo-like kinase 1 in the regulation of the action of p31(comet) in the disassembly of mitotic checkpoint complexes

The Mad2-binding protein p31(comet) has important roles in the inactivation of the mitotic checkpoint system, which delays anaphase until chromosomes attach correctly to the mitotic spindle. The activation of the checkpoint promotes the assembly of a Mitotic Checkpoint Complex (MCC), which inhibits...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kaisari, Sharon, Shomer, Pnina, Ziv, Tamar, Sitry-Shevah, Danielle, Miniowitz-Shemtov, Shirly, Teichner, Adar, Hershko, Avram
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575526/
https://ncbi.nlm.nih.gov/pubmed/31118282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902970116
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