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Role of phosphorylation of Cdc20 in p31(comet)-stimulated disassembly of the mitotic checkpoint complex

The mitotic checkpoint system delays anaphase until all chromosomes are correctly attached to the mitotic spindle. When the checkpoint is turned on, it promotes the formation of the mitotic checkpoint complex (MCC), which inhibits the ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C). MC...

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Auteurs principaux: Miniowitz-Shemtov, Shirly, Eytan, Esther, Ganoth, Dvora, Sitry-Shevah, Danielle, Dumin, Elena, Hershko, Avram
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361403/
https://ncbi.nlm.nih.gov/pubmed/22566641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204081109
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