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Intermediates in the assembly of mitotic checkpoint complexes and their role in the regulation of the anaphase-promoting complex

The mitotic (or spindle assembly) checkpoint system prevents premature separation of sister chromatids in mitosis and thus ensures the fidelity of chromosome segregation. Kinetochores that are not attached properly to the mitotic spindle produce an inhibitory signal that prevents progression into an...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Kaisari, Sharon, Sitry-Shevah, Danielle, Miniowitz-Shemtov, Shirly, Hershko, Avram
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743829/
https://ncbi.nlm.nih.gov/pubmed/26755599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524551113
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