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Intermediates in the assembly of mitotic checkpoint complexes and their role in the regulation of the anaphase-promoting complex

The mitotic (or spindle assembly) checkpoint system prevents premature separation of sister chromatids in mitosis and thus ensures the fidelity of chromosome segregation. Kinetochores that are not attached properly to the mitotic spindle produce an inhibitory signal that prevents progression into an...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Kaisari, Sharon, Sitry-Shevah, Danielle, Miniowitz-Shemtov, Shirly, Hershko, Avram
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743829/
https://ncbi.nlm.nih.gov/pubmed/26755599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524551113
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