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BK channel β1-subunit deficiency exacerbates vascular fibrosis and remodeling but does not promote hypertension in high fat fed obesity in mice
OBJECTIVE: Reduced expression or increased degradation of BK (large conductance Ca(2+)-activated K(+)) channel β1-subunits has been associated with increased vascular tone and hypertension in some metabolic diseases. The contribution of BK channel function to control of blood pressure (BP), heart ra...
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| Udgivet i: | J Hypertens |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4743538/ https://ncbi.nlm.nih.gov/pubmed/26049174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0000000000000590 |
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