Western blot analysis of BK channel β1‐subunit expression should be interpreted cautiously when using commercially available antibodies

Large conductance Ca(2+)‐activated K(+) (BK) channels consist of pore‐forming α‐ and accessory β‐subunits. There are four β‐subunit subtypes (β1–β4), BK β1‐subunit is specific for smooth muscle cells (SMC). Reduced BK β1‐subunit expression is associated with SMC dysfunction in animal models of human...

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Udgivet i:Physiol Rep
Main Authors: Bhattarai, Yogesh, Fernandes, Roxanne, Kadrofske, Mark M., Lockwood, Lizbeth R., Galligan, James J., Xu, Hui
Format: Artigo
Sprog:Inglês
Udgivet: Wiley Periodicals, Inc. 2014
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254108/
https://ncbi.nlm.nih.gov/pubmed/25355855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12189
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