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Western blot analysis of BK channel β1‐subunit expression should be interpreted cautiously when using commercially available antibodies

Large conductance Ca(2+)‐activated K(+) (BK) channels consist of pore‐forming α‐ and accessory β‐subunits. There are four β‐subunit subtypes (β1–β4), BK β1‐subunit is specific for smooth muscle cells (SMC). Reduced BK β1‐subunit expression is associated with SMC dysfunction in animal models of human...

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Vydáno v:Physiol Rep
Hlavní autoři: Bhattarai, Yogesh, Fernandes, Roxanne, Kadrofske, Mark M., Lockwood, Lizbeth R., Galligan, James J., Xu, Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Periodicals, Inc. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254108/
https://ncbi.nlm.nih.gov/pubmed/25355855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12189
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