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Western blot analysis of BK channel β1‐subunit expression should be interpreted cautiously when using commercially available antibodies

Large conductance Ca(2+)‐activated K(+) (BK) channels consist of pore‐forming α‐ and accessory β‐subunits. There are four β‐subunit subtypes (β1–β4), BK β1‐subunit is specific for smooth muscle cells (SMC). Reduced BK β1‐subunit expression is associated with SMC dysfunction in animal models of human...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Physiol Rep
Prif Awduron: Bhattarai, Yogesh, Fernandes, Roxanne, Kadrofske, Mark M., Lockwood, Lizbeth R., Galligan, James J., Xu, Hui
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Wiley Periodicals, Inc. 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254108/
https://ncbi.nlm.nih.gov/pubmed/25355855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12189
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