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Western blot analysis of BK channel β1‐subunit expression should be interpreted cautiously when using commercially available antibodies

Large conductance Ca(2+)‐activated K(+) (BK) channels consist of pore‐forming α‐ and accessory β‐subunits. There are four β‐subunit subtypes (β1–β4), BK β1‐subunit is specific for smooth muscle cells (SMC). Reduced BK β1‐subunit expression is associated with SMC dysfunction in animal models of human...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Bhattarai, Yogesh, Fernandes, Roxanne, Kadrofske, Mark M., Lockwood, Lizbeth R., Galligan, James J., Xu, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254108/
https://ncbi.nlm.nih.gov/pubmed/25355855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12189
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