Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis

Autophagy is a conserved, intracellular, lysosomal degradation pathway. While mechanistic aspects of this pathway are increasingly well defined, it remains unclear how autophagy modulation impacts normal physiology. It is, however, becoming clear that autophagy may play a key role in regulating deve...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Wu, Xiaoting, Fleming, Angeleen, Ricketts, Thomas, Pavel, Mariana, Virgin, Herbert, Menzies, Fiona M., Rubinsztein, David C.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742842/
https://ncbi.nlm.nih.gov/pubmed/26837467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10533
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