Polyglutamine tracts regulate autophagy

Expansions of polyglutamine (polyQ) tracts in different proteins cause 9 neurodegenerative conditions, such as Huntington disease and various ataxias. However, many normal mammalian proteins contain shorter polyQ tracts. As these are frequently conserved in multiple species, it is likely that some o...

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Detalles Bibliográficos
Publicado en:Autophagy
Autores principales: Ashkenazi, Avraham, Bento, Carla F., Ricketts, Thomas, Vicinanza, Mariella, Siddiqi, Farah, Pavel, Mariana, Squitieri, Ferdinando, Hardenberg, Maarten C., Imarisio, Sara, Menzies, Fiona M., Rubinsztein, David C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2017
Materias:
Autophagic Puncta
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612341/
https://ncbi.nlm.nih.gov/pubmed/28722507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1336278
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