Polyglutamine tracts regulate autophagy

Expansions of polyglutamine (polyQ) tracts in different proteins cause 9 neurodegenerative conditions, such as Huntington disease and various ataxias. However, many normal mammalian proteins contain shorter polyQ tracts. As these are frequently conserved in multiple species, it is likely that some o...

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Détails bibliographiques
Publié dans:Autophagy
Auteurs principaux: Ashkenazi, Avraham, Bento, Carla F., Ricketts, Thomas, Vicinanza, Mariella, Siddiqi, Farah, Pavel, Mariana, Squitieri, Ferdinando, Hardenberg, Maarten C., Imarisio, Sara, Menzies, Fiona M., Rubinsztein, David C.
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2017
Sujets:
Autophagic Puncta
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612341/
https://ncbi.nlm.nih.gov/pubmed/28722507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1336278
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