Polyglutamine tracts regulate autophagy

Expansions of polyglutamine (polyQ) tracts in different proteins cause 9 neurodegenerative conditions, such as Huntington disease and various ataxias. However, many normal mammalian proteins contain shorter polyQ tracts. As these are frequently conserved in multiple species, it is likely that some o...

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Bibliographic Details
Published in:Autophagy
Main Authors: Ashkenazi, Avraham, Bento, Carla F., Ricketts, Thomas, Vicinanza, Mariella, Siddiqi, Farah, Pavel, Mariana, Squitieri, Ferdinando, Hardenberg, Maarten C., Imarisio, Sara, Menzies, Fiona M., Rubinsztein, David C.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2017
Subjects:
Autophagic Puncta
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612341/
https://ncbi.nlm.nih.gov/pubmed/28722507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1336278
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