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Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis

Autophagy is a conserved, intracellular, lysosomal degradation pathway. While mechanistic aspects of this pathway are increasingly well defined, it remains unclear how autophagy modulation impacts normal physiology. It is, however, becoming clear that autophagy may play a key role in regulating deve...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wu, Xiaoting, Fleming, Angeleen, Ricketts, Thomas, Pavel, Mariana, Virgin, Herbert, Menzies, Fiona M., Rubinsztein, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742842/
https://ncbi.nlm.nih.gov/pubmed/26837467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10533
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