Wird geladen...
Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth
In soft tissue sarcomas (STS), low intratumoural O(2) (hypoxia) is a poor prognostic indicator. HIF-1α mediates key transcriptional responses to hypoxia, and promotes STS metastasis; however, the role of the related HIF-2α protein is unknown. Surprisingly, here we show that HIF-2α inhibits high-grad...
Gespeichert in:
| Veröffentlicht in: | Nat Commun |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4742834/ https://ncbi.nlm.nih.gov/pubmed/26837714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10539 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|