Učitavanje...
Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth
In soft tissue sarcomas (STS), low intratumoural O(2) (hypoxia) is a poor prognostic indicator. HIF-1α mediates key transcriptional responses to hypoxia, and promotes STS metastasis; however, the role of the related HIF-2α protein is unknown. Surprisingly, here we show that HIF-2α inhibits high-grad...
Spremljeno u:
Izdano u: | Nat Commun |
---|---|
Glavni autori: | , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Nature Publishing Group
2016
|
Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4742834/ https://ncbi.nlm.nih.gov/pubmed/26837714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10539 |
Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|