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Ras Regulates Rb via NORE1A

Mutations in the Ras oncogene are one of the most frequent events in human cancer. Although Ras regulates numerous growth-promoting pathways to drive transformation, it can paradoxically promote an irreversible cell cycle arrest known as oncogene-induced senescence. Although senescence has clearly b...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Barnoud, Thibaut, Donninger, Howard, Clark, Geoffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742771/
https://ncbi.nlm.nih.gov/pubmed/26677227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.697557
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