Progesterone-induced Acrosome Exocytosis Requires Sequential Involvement of Calcium-independent Phospholipase A(2)β (iPLA(2)β) and Group X Secreted Phospholipase A(2) (sPLA(2))

Phospholipase A(2) (PLA(2)) activity has been shown to be involved in the sperm acrosome reaction (AR), but the molecular identity of PLA(2) isoforms has remained elusive. Here, we have tested the role of two intracellular (iPLA(2)β and cytosolic PLA(2)α) and one secreted (group X) PLA(2)s in sponta...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Abi Nahed, Roland, Martinez, Guillaume, Escoffier, Jessica, Yassine, Sandra, Karaouzène, Thomas, Hograindleur, Jean-Pascal, Turk, John, Kokotos, George, Ray, Pierre F., Bottari, Serge, Lambeau, Gérard, Hennebicq, Sylviane, Arnoult, Christophe
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Lipids
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742768/
https://ncbi.nlm.nih.gov/pubmed/26655718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.677799
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