Progesterone-induced Acrosome Exocytosis Requires Sequential Involvement of Calcium-independent Phospholipase A(2)β (iPLA(2)β) and Group X Secreted Phospholipase A(2) (sPLA(2))

Phospholipase A(2) (PLA(2)) activity has been shown to be involved in the sperm acrosome reaction (AR), but the molecular identity of PLA(2) isoforms has remained elusive. Here, we have tested the role of two intracellular (iPLA(2)β and cytosolic PLA(2)α) and one secreted (group X) PLA(2)s in sponta...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Abi Nahed, Roland, Martinez, Guillaume, Escoffier, Jessica, Yassine, Sandra, Karaouzène, Thomas, Hograindleur, Jean-Pascal, Turk, John, Kokotos, George, Ray, Pierre F., Bottari, Serge, Lambeau, Gérard, Hennebicq, Sylviane, Arnoult, Christophe
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Lipids
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742768/
https://ncbi.nlm.nih.gov/pubmed/26655718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.677799
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