Progesterone-induced Acrosome Exocytosis Requires Sequential Involvement of Calcium-independent Phospholipase A(2)β (iPLA(2)β) and Group X Secreted Phospholipase A(2) (sPLA(2))

Phospholipase A(2) (PLA(2)) activity has been shown to be involved in the sperm acrosome reaction (AR), but the molecular identity of PLA(2) isoforms has remained elusive. Here, we have tested the role of two intracellular (iPLA(2)β and cytosolic PLA(2)α) and one secreted (group X) PLA(2)s in sponta...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Abi Nahed, Roland, Martinez, Guillaume, Escoffier, Jessica, Yassine, Sandra, Karaouzène, Thomas, Hograindleur, Jean-Pascal, Turk, John, Kokotos, George, Ray, Pierre F., Bottari, Serge, Lambeau, Gérard, Hennebicq, Sylviane, Arnoult, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742768/
https://ncbi.nlm.nih.gov/pubmed/26655718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.677799
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