Progesterone-induced Acrosome Exocytosis Requires Sequential Involvement of Calcium-independent Phospholipase A(2)β (iPLA(2)β) and Group X Secreted Phospholipase A(2) (sPLA(2))

Phospholipase A(2) (PLA(2)) activity has been shown to be involved in the sperm acrosome reaction (AR), but the molecular identity of PLA(2) isoforms has remained elusive. Here, we have tested the role of two intracellular (iPLA(2)β and cytosolic PLA(2)α) and one secreted (group X) PLA(2)s in sponta...

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Vydáno v:J Biol Chem
Hlavní autoři: Abi Nahed, Roland, Martinez, Guillaume, Escoffier, Jessica, Yassine, Sandra, Karaouzène, Thomas, Hograindleur, Jean-Pascal, Turk, John, Kokotos, George, Ray, Pierre F., Bottari, Serge, Lambeau, Gérard, Hennebicq, Sylviane, Arnoult, Christophe
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Lipids
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742768/
https://ncbi.nlm.nih.gov/pubmed/26655718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.677799
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