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Targeting ERK1/2-bim signaling cascades by BH3-mimetic ABT-737 as an alternative therapeutic strategy for oral cancer

To date, many different chemotherapeutic agents have been widely used as common treatments for oral cancers. However, their therapeutic effects have been disappointing, and these agents may have unwanted side effects. Among the many regulatory factors, overexpression of pro-survival Bcl-2 family mem...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Shin, Ji-Ae, Kim, Lee-Han, Lee, Sook-Jeong, Jeong, Joseph H., Jung, Ji-Youn, Lee, Hae Nim, Hong, In-Sun, Cho, Sung-Dae
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742133/
https://ncbi.nlm.nih.gov/pubmed/26447615
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