Usp22 deficiency impairs intestinal epithelial lineage specification in vivo

Epigenetic regulatory mechanisms play a central role in controlling gene expression during development, cell differentiation and tumorigenesis. Monoubiquitination of histone H2B is one epigenetic modification which is dynamically regulated by the opposing activities of specific ubiquitin ligases and...

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Udgivet i:Oncotarget
Main Authors: Kosinsky, Robyn L., Wegwitz, Florian, Hellbach, Nicole, Dobbelstein, Matthias, Mansouri, Ahmed, Vogel, Tanja, Begus-Nahrmann, Yvonne, Johnsen, Steven A.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741973/
https://ncbi.nlm.nih.gov/pubmed/26431380
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