Reciprocal regulation of Abl kinase by Crk Y251 and Abi1 controls invasive phenotypes in glioblastoma

Crk is the prototypical member of a class of Src homology 2 (SH2) and Src homology 3 (SH3) domain-containing adaptor proteins that positively regulate cell motility via the activation of Rac1 and, in certain tumor types such as GBM, can promote cell invasion and metastasis by mechanisms that are not...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kumar, Sushil, Lu, Bin, Dixit, Updesh, Hossain, Sajjad, Liu, Yongzhang, Li, Jing, Hornbeck, Peter, Zheng, Weiming, Sowalsky, Adam G., Kotula, Leszek, Birge, Raymond B.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741966/
https://ncbi.nlm.nih.gov/pubmed/26473374
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