Wird geladen...
Cyclophilin A promotes cell migration via the Abl-Crk signaling pathway
Cyclophilin A (CypA) is over-expressed in a number of human cancer types, but the mechanisms by which CypA promotes oncogenic properties of cells are not understood. Here we demonstrate that CypA binds to and prevents the CrkII adaptor protein from switching to the inhibited state. CrkII is involved...
Gespeichert in:
| Veröffentlicht in: | Nat Chem Biol |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4718742/ https://ncbi.nlm.nih.gov/pubmed/26656091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1981 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|