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Structural basis for regulation of the Crk signaling protein by a proline switch
Proline switches, controlled by cis–trans isomerization, have emerged as a particularly effective regulatory mechanism in a wide range of biological processes. Here we report the structures of both the cis and trans conformers of a proline switch in Crk signaling protein. Proline isomerization toggl...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039521/ https://ncbi.nlm.nih.gov/pubmed/21131971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.494 |
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