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Proline cis-trans isomerization controls autoinhibition of a signaling protein
Autoinhibition is being widely used in nature to repress otherwise constitutive protein activities and is typically regulated by extrinsic factors. Here we show that autoinhibition can be controlled by an intrinsic intramolecular switch afforded by prolyl cis-trans isomerization. We find that a prol...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2007
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2566824/ https://ncbi.nlm.nih.gov/pubmed/17289588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.01.004 |
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