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Molecular Dynamics of the Proline Switch and Its Role in Crk Signaling

[Image: see text] The Crk adaptor proteins play a central role as a molecular timer for the formation of protein complexes including various growth and differentiation factors. The loss of regulation of Crk results in many kinds of cancers. A self-regulatory mechanism for Crk was recently proposed,...

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Detalhes bibliográficos
Main Authors: Xia, Junchao, Levy, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007982/
https://ncbi.nlm.nih.gov/pubmed/24702481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp5013297
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